Science fiction is clear that our future includes conversations with our machines; think of HAL or the Star Trek computer. In 2005, the Clarissa Procedure Assistant made a step toward that future, when its use on the ISS made it the first spoken dialogue system in space. Dr. Beth Ann Hockey, project lead for Clarissa, will describe the science and technology behind that system, and examine uses of this technology in space and on earth, interacting with robots, wheelchairs, cars and software. Dr.